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Your thoughts and beliefs aren't real
Purpose, meaning, spirituality, religion, motivation, goals, dreams, aspirations. If you really think about it are all fabrications. Man-made, and predominantly in your head, things not of the physical world. I would say that anything your mind can think up isn't real. Go with me on this.
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I've developed depression
I have developed depression from my workplace. I don't feel valued by the company and they have made it pretty clear that my future there is stagnant without changing my role or climbing the corporate ladder. I'm a creative, and have never wanted to become a suit at a desk. You know those corporate suits that justify their existence by how many meetings they have to go to. No thanks, that's not for me.